Phosphoenolpyruvate counteracts the decrease in adenylate energy charge induced by a calcium ionophore, A23187.
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چکیده
منابع مشابه
Calcium-dependent shortening of fibroblasts induced by the ionophore, A23187.
Attached, spread, chick heart fibroblasts were induced to shorten by treatment with the ionophore, A23187. The shortening resulted from the retraction of the leading lamellae and other major cell processes. The response was dependent on external calcium with a threshold close to, and a maximal effect at, physiological concentrations. The shortening was also induced in Colcemid-treated cells and...
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Concentrations of the divalent cation ionophore, A23187, optimal for the transformation of human and pig lymphocytes, were cytotoxic to lymphocytes from rats and mice. The biochemical effects associated with A23187-induced cytolysis in rat thymocytes included inhibition of [3H]uridine uptake and incorporation into macromolecules and stimulation of [14C]-alpha-aminoisobutyric acid uptake. The bi...
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We have recently reported that acetylcholinesterase expression was induced during apoptosis in various cell types. In the current study we provide evidence to suggest that the induction of acetylcholinesterase expression during apoptosis is regulated by the mobilization of intracellular Ca(2+). During apoptosis, treatment of HeLa and MDA-MB-435s cells with the calcium ionophore A23187 resulted ...
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This study was designated to clarify the influence of activation of porcine matured oocytes by calcium ionophore on in vitro development of the parthenotes. The follicular oocytes were matured, activated and cultured in North Carolina State University-23 (NCSU-23) medium supplemented with 10% porcine follicular fluid (pFF). The in vitro-matured oocytes were exposed to calcium ionophore at conce...
متن کاملRegulation at the phosphoenolpyruvate branchpoint by the adenylate energy charge in Mytilus edulis.
Pyruvate kinase (EC 2.7.1.40) is an enzyme with high activity in most tissues. Phosphoenolpyruvate carboxykinase (EC 4.1 .I .32) always has a restricted distribution. In vertebrates phosphoenolpyruvate carboxykinase is found in tissues, such as liver and kidney cortex, with highgluconeogenicactivities (Scrutton & Utter, 1968). In thesetissues the enzyme operates together with pyruvate carboxyla...
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ژورنال
عنوان ژورنال: Journal of the Japan Society of Blood Transfusion
سال: 1990
ISSN: 1883-8383,0546-1448
DOI: 10.3925/jjtc1958.36.424